Basic Information
ID: ALA5246538
Type: Binding
Description: Modulation of P-glycoprotein mediated Rhodamine-123 efflux in multi-drug resistant mouse L5178Y cells tranfected with ABCB1 gene assessed as fluorescence activity ratio at 2 uM preincubated for 10 mins followed by rhodamine-123 addition and measured after 20 mins by flow cytometric analysis (Rvb = 1.01 No_unit)
Format: BAO_0000219
Organism: Mus musculus
Cell type: L5178Y
Target: Unchecked(ALA612545)
Document: ALA5244266
Modulation of P-glycoprotein mediated Rhodamine-123 efflux in multi-drug resistant mouse L5178Y cells tranfected with ABCB1 gene assessed as fluorescence activity ratio at 2 uM preincubated for 10 mins followed by rhodamine-123 addition and measured after 20 mins by flow cytometric analysis (Rvb = 1.01 No_unit): 1
Activity Charts
Bioactivity
Activity Types for Assay ALA5246538
Ratio
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 272.26 | 2.51 | 2.51 |
| 286.28 | 2.81 | 2.81 |
| 300.31 | 3.12 | 3.12 |
| 443.46 | 3.87 | 3.87 |
| 420.42 | 3.96 | 3.96 |
| 459.50 | 4.57 | 4.57 |
| 378.81 | 3.09 | 3.09 |
| 394.38 | 3.36 | 3.36 |
| 413.43 | 4.63 | 4.63 |
| 390.44 | 4.75 | 4.75 |
| 472.42 | 4.78 | 4.78 |
| 419.44 | 3.35 | 3.35 |
| 314.34 | 2.60 | 2.60 |
| 408.41 | 3.66 | 3.66 |
| 342.35 | 2.88 | 2.88 |
| 433.46 | 3.65 | 3.65 |
| 410.45 | 3.83 | 3.83 |
| 442.27 | 4.30 | 4.30 |
| 373.43 | 2.47 | 2.47 |
| 448.48 | 4.56 | 4.56 |
| 456.30 | 4.60 | 4.60 |
| 470.32 | 4.91 | 4.91 |
| 300.31 | 2.29 | 2.29 |
| 362.39 | 4.14 | 4.14 |
| 377.40 | 3.49 | 3.49 |
| 457.49 | 4.17 | 4.17 |
| 452.53 | 4.64 | 4.64 |
| 364.36 | 2.93 | 2.93 |
| 427.50 | 3.33 | 3.33 |
| 418.45 | 4.46 | 4.46 |
| 286.29 | 1.99 | 1.99 |
| 396.42 | 3.52 | 3.52 |
| 415.49 | 3.19 | 3.19 |
| 532.64 | 4.10 | 4.10 |
| 434.45 | 4.26 | 4.26 |
| 471.51 | 4.48 | 4.48 |
| 485.53 | 2.73 | 2.73 |
| 376.41 | 4.45 | 4.45 |
| 380.36 | 3.05 | 3.05 |