Basic Information
ID: ALA5246541
Type: Binding
Description: Modulation of P-glycoprotein mediated Rhodamine-123 efflux in multi-drug resistant mouse L5178Y cells tranfected with ABCB1 gene assessed as fluorescence activity ratio by measuring fold change at 2 uM preincubated for 10 mins followed by rhodamine-123 addition and measured after 20 mins by flow cytometric analysis relative to verapamil
Format: BAO_0000219
Organism: Mus musculus
Cell type: L5178Y
Target: Unchecked(ALA612545)
Document: ALA5244266
Modulation of P-glycoprotein mediated Rhodamine-123 efflux in multi-drug resistant mouse L5178Y cells tranfected with ABCB1 gene assessed as fluorescence activity ratio by measuring fold change at 2 uM preincubated for 10 mins followed by rhodamine-123 addition and measured after 20 mins by flow cytometric analysis relative to verapamil: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA5246541
FC
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 532.64 | 4.10 | 4.10 |