Basic Information
ID: ALA5246747
Type: Binding
Description: Selectivity ratio of IC50 for inhibition of N-terminal GST-fused human wild type LRRK2 to IC50 for inhibition of N-terminal GST-fused human wild type LRRK2 G2019S mutant
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA5246747
Ratio IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 353.35 | 0.01 | 0.01 |
| 324.35 | 1.22 | 1.22 |
| 324.35 | 1.30 | 1.30 |
| 409.45 | 0.61 | 0.61 |
| 500.57 | 2.55 | 2.55 |
| 350.39 | 1.73 | 1.73 |
| 389.22 | 1.67 | 1.67 |
| 324.35 | 0.94 | 0.94 |
| 473.50 | 1.21 | 1.21 |
| 354.37 | 0.78 | 0.78 |
| 367.37 | 0.96 | 0.96 |
| 353.34 | 0.48 | 0.48 |
| 324.35 | 1.47 | 1.47 |
| 354.37 | 0.78 | 0.78 |
| 472.51 | 1.81 | 1.81 |
| 296.29 | 0.52 | 0.52 |
| 387.41 | 1.97 | 1.97 |
| 310.32 | 0.91 | 0.91 |
| 338.38 | 1.78 | 1.78 |
| 338.38 | 1.78 | 1.78 |
| 395.43 | 1.65 | 1.65 |
| 414.47 | 3.31 | 3.31 |
| 323.36 | 1.83 | 1.83 |
| 352.40 | 1.96 | 1.96 |
| 486.54 | 2.37 | 2.37 |
| 326.32 | 0.21 | 0.21 |
| 338.33 | 0.83 | 0.83 |
| 324.35 | 1.30 | 1.30 |
| 465.50 | 1.23 | 1.23 |
| 325.33 | 0.53 | 0.53 |
| 326.39 | 1.71 | 1.71 |
| 324.35 | 0.99 | 0.99 |
| 372.39 | 2.61 | 2.61 |
| 401.43 | 2.53 | 2.53 |
| 324.35 | 0.99 | 0.99 |
| 339.36 | 0.84 | 0.84 |
| 429.44 | 2.16 | 2.16 |
| 426.44 | 2.46 | 2.46 |
| 338.38 | 1.65 | 1.65 |
| 324.35 | 1.47 | 1.47 |
| 486.54 | 2.37 | 2.37 |
| 310.32 | 0.91 | 0.91 |