Basic Information
ID: ALA5246749
Type: Binding
Description: Inhibition of human LRRK2 G2019S mutant expressed in HEK293 cells assessed as reduction in pSer935 phosphorylation incubated for 2 hrs by HTRF analysis
Organism: Homo sapiens
Cell type: HEK293
Activity Charts
Bioactivity
Activity Types for Assay ALA5246749
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 500.57 | 2.55 | 2.55 |
| 472.51 | 1.81 | 1.81 |
| 338.38 | 1.78 | 1.78 |
| 414.47 | 3.31 | 3.31 |
| 486.54 | 2.37 | 2.37 |
| 401.43 | 2.53 | 2.53 |
| 426.44 | 2.46 | 2.46 |
| 324.35 | 1.47 | 1.47 |