Basic Information
ID: ALA5246753
Type: Binding
Description: Selectivity ratio of IC50 for inhibition of human wild type LRRK2 expressed in HEK293 cells assessed as reduction in pSer935 phosphorylation to IC50 for inhibition of human LRRK2 G2019S mutant expressed in HEK293 cells assessed as reduction in pSer935 phosphorylation
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA5246753
Ratio IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 500.57 | 2.55 | 2.55 |
| 338.38 | 1.78 | 1.78 |
| 414.47 | 3.31 | 3.31 |