Basic Information
ID: ALA5246758
Type: Binding
Description: Inhibition human LRRK2 G2019S mutant expressed in human HEK293 assessed as Rab10 substrate phosphorylation at Threonine 73 residue incubated for 2 hrs by immunoblotting analysis
Organism: Homo sapiens
Cell type: HEK293
Activity Charts
Bioactivity
Activity Types for Assay ALA5246758
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 500.57 | 2.55 | 2.55 |
| 472.51 | 1.81 | 1.81 |
| 338.38 | 1.78 | 1.78 |
| 414.47 | 3.31 | 3.31 |
| 486.54 | 2.37 | 2.37 |
| 401.43 | 2.53 | 2.53 |
| 426.44 | 2.46 | 2.46 |
| 324.35 | 1.47 | 1.47 |