Basic Information
ID: ALA5246759
Type: Binding
Description: Selectivity ratio of IC50 for inhibition human wild type LRRK2 expressed in human HEK293 assessed as Rab10 substrate phosphorylation at Threonine 73 residue to IC50 for inhibition of human LRRK2 G2019S mutant expressed in human HEK293 assessed as Rab10 substrate phosphorylation at Threonine 73 residue
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA5246759
Ratio IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 500.57 | 2.55 | 2.55 |
| 472.51 | 1.81 | 1.81 |
| 338.38 | 1.78 | 1.78 |
| 414.47 | 3.31 | 3.31 |
| 486.54 | 2.37 | 2.37 |
| 401.43 | 2.53 | 2.53 |
| 426.44 | 2.46 | 2.46 |
| 324.35 | 1.47 | 1.47 |