Basic Information
ID: ALA5247164
Type: Binding
Description: Displacement of [3H]spermidine trihydrochloride from N-terminal 6his tagged TEV fused human DHPS expressed in Escherichia coli BL21 (DE3) incubated for 120 mins in the presence of 14 uM NAD+ by radiometric assay
Format: BAO_0000019
Organism: Homo sapiens
Target: Deoxyhypusine synthase(ALA4415)
Document: ALA5244276
Displacement of [3H]spermidine trihydrochloride from N-terminal 6his tagged TEV fused human DHPS expressed in Escherichia coli BL21 (DE3) incubated for 120 mins in the presence of 14 uM NAD+ by radiometric assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA5247164
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 371.26 | 5.40 | 5.40 |
| 329.47 | 3.18 | 3.18 |
| 405.55 | 4.72 | 4.72 |
| 315.44 | 2.94 | 2.94 |
| 320.42 | 4.01 | 4.01 |
| 349.46 | 3.51 | 3.51 |
| 378.45 | 3.72 | 3.72 |
| 361.47 | 3.65 | 3.65 |
| 319.39 | 3.57 | 3.57 |
| 314.39 | 3.95 | 3.95 |
| 349.46 | 3.51 | 3.51 |
| 312.37 | 4.11 | 4.11 |
| 357.52 | 4.11 | 4.11 |
| 300.36 | 3.90 | 3.90 |
| 329.47 | 3.18 | 3.18 |
| 350.44 | 3.54 | 3.54 |
| 314.39 | 3.95 | 3.95 |
| 388.50 | 3.99 | 3.99 |
| 363.49 | 3.90 | 3.90 |
| 324.41 | 3.27 | 3.27 |
| 349.46 | 3.51 | 3.51 |
| 355.51 | 3.72 | 3.72 |