Basic Information
ID: ALA5248044
Type: Binding
Description: Inhibition of human recombinant his tagged HDAC1 expressed in baculovirus expression system using FLUOR DE LYS-SIRT1 as fluorogenic substrate preincubated for 10 mins followed by substrate addition and measured after 1 hr by spectrophotometer based analysis
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA5248044
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 550.70 | 7.36 | 7.36 |
| 492.61 | 4.26 | 4.26 |
| 461.59 | 4.85 | 4.85 |
| 477.59 | 3.89 | 3.89 |
| 540.67 | 4.78 | 4.78 |
| 496.58 | 4.64 | 4.64 |
| 539.68 | 4.52 | 4.52 |
| 494.64 | 5.33 | 5.33 |
| 522.60 | 3.84 | 3.84 |
| 478.59 | 4.55 | 4.55 |
| 468.63 | 3.76 | 3.76 |
| 447.58 | 5.14 | 5.14 |
| 537.67 | 5.23 | 5.23 |
| 464.57 | 3.83 | 3.83 |
| 518.66 | 5.47 | 5.47 |
| 528.70 | 5.11 | 5.11 |
| 551.69 | 7.62 | 7.62 |
| 446.60 | 4.88 | 4.88 |
| 490.56 | 4.28 | 4.28 |
| 492.58 | 4.12 | 4.12 |