Basic Information
ID: ALA5248749
Type: Binding
Description: Inhibition of human URAT1 mediated 14C-uric acid uptake expressed in HEK293 cells using 14C-uric acid as substrate incubated for 30 mins by liquid scintillation counting analysis
Organism: Homo sapiens
Cell type: HEK293
Activity Charts
Bioactivity
Activity Types for Assay ALA5248749
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 404.29 | 4.24 | 4.24 |
| 622.36 | 5.42 | 5.42 |
| 370.43 | 3.22 | 3.22 |
| 547.68 | 5.08 | 5.08 |
| 344.39 | 2.69 | 2.69 |
| 511.65 | 4.18 | 4.18 |
| 358.42 | 3.08 | 3.08 |
| 513.67 | 4.42 | 4.42 |
| 615.68 | 6.09 | 6.09 |
| 563.68 | 4.78 | 4.78 |
| 408.50 | 4.65 | 4.65 |
| 358.42 | 3.08 | 3.08 |
| 603.79 | 6.37 | 6.37 |
| 592.68 | 4.98 | 4.98 |
| 583.66 | 5.35 | 5.35 |
| 485.61 | 3.65 | 3.65 |
| 588.16 | 5.79 | 5.79 |
| 356.45 | 3.24 | 3.24 |
| 592.68 | 4.98 | 4.98 |
| 342.42 | 2.85 | 2.85 |
| 582.13 | 5.73 | 5.73 |
| 328.39 | 2.46 | 2.46 |
| 344.39 | 2.69 | 2.69 |
| 626.58 | 5.84 | 5.84 |
| 592.68 | 4.98 | 4.98 |
| 527.69 | 4.81 | 4.81 |
| 583.66 | 5.35 | 5.35 |
| 356.45 | 3.24 | 3.24 |
| 499.64 | 4.04 | 4.04 |
| 342.42 | 2.85 | 2.85 |
| 330.37 | 2.30 | 2.30 |
| 368.46 | 3.38 | 3.38 |
| 565.67 | 5.21 | 5.21 |