Basic Information
ID: ALA5248836
Type: Functional
Description: Antiproliferative activity against human NCI-H23 cells harboring KRAS G12C mutant assessed as reduction in cell viability incubated for 72 hrs by MTT assay
Organism: Homo sapiens
Cell type: NCI-H23
Activity Charts
Bioactivity
Activity Types for Assay ALA5248836
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 513.79 | 2.42 | 2.42 |
| 330.22 | 2.69 | 2.69 |
| 307.78 | 2.64 | 2.64 |
| 471.68 | 2.30 | 2.30 |
| 328.20 | 2.90 | 2.90 |
| 325.37 | 1.43 | 1.43 |
| 361.75 | 3.27 | 3.27 |
| 361.75 | 3.27 | 3.27 |
| 521.76 | 2.45 | 2.45 |
| 508.14 | 2.75 | 2.75 |
| 398.21 | 3.71 | 3.71 |
| 424.30 | 4.50 | 4.50 |
| 293.75 | 2.25 | 2.25 |
| 410.28 | 4.06 | 4.06 |
| 494.12 | 2.36 | 2.36 |
| 343.84 | 2.40 | 2.40 |
| 411.83 | 3.42 | 3.42 |
| 485.71 | 2.69 | 2.69 |
| 364.66 | 3.34 | 3.34 |
| 342.23 | 3.29 | 3.29 |
| 471.68 | 2.30 | 2.30 |
| 454.33 | 4.51 | 4.51 |
| 384.19 | 3.32 | 3.32 |
| 293.75 | 2.25 | 2.25 |
| 375.78 | 3.66 | 3.66 |
| 328.20 | 2.90 | 2.90 |
| 384.19 | 3.32 | 3.32 |
| 427.81 | 3.11 | 3.11 |
| 359.81 | 2.09 | 2.09 |
| 384.19 | 3.27 | 3.27 |