Basic Information
ID: ALA5248852
Type: Binding
Description: Inhibition of KRAS signaling in human NCI-H358 cells harboring KRAS G12C mutant assessed as decrease in ERK phosphorylation level at 0.5 to 8 uM incubated for 6 hrs by Western blot analysis relative to control
Organism: Homo sapiens
Cell type: NCI-H358
Activity Charts
Bioactivity
Activity Types for Assay ALA5248852
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 410.28 | 4.06 | 4.06 |