Assay Report Card

Basic Information

ID: ALA5248859

Type: Functional

Description: Antitumor activity against human NCI-H358 cells harboring KRAS G12C mutant xenografted in BALB/c mouse assessed as increase in cleaved caspase-3 level at 10 to 15 mg/kg, ip administered for 21 days by IHC staining analysis

Organism: Homo sapiens

Cell type: NCI-H358

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
410.284.064.06