Basic Information
ID: ALA5248859
Type: Functional
Description: Antitumor activity against human NCI-H358 cells harboring KRAS G12C mutant xenografted in BALB/c mouse assessed as increase in cleaved caspase-3 level at 10 to 15 mg/kg, ip administered for 21 days by IHC staining analysis
Organism: Homo sapiens
Cell type: NCI-H358
Activity Charts
Bioactivity
Activity Types for Assay ALA5248859
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 410.28 | 4.06 | 4.06 |