Basic Information
ID: ALA5248886
Type: Functional
Description: Invivo inhibition of STING in BALB/c mouse model of LPS induced sepsis assessed as inhibition of upregulation of phosphorylated TBK1 mRNA expression at 1.25 to 5 mg/kg, IG administered once a day for 3 days followed by LPS stimulation for 12 hrs starting from 2 hrs post last dose by Western blot analysis
Organism: Mus musculus
Strain: BALB/c
Activity Charts
Bioactivity
Activity Types for Assay ALA5248886
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 854.18 | 9.27 | 9.27 |