PROTAC activity at VHL/VEGFR2 in human HGC-27 cells assessed as induction of VEGRF2 protein degradation at 1 uM preincubated with 4-Amino-N-(6-(1-(2-(...

ID: ALA5249114

Type: Binding

Description: PROTAC activity at VHL/VEGFR2 in human HGC-27 cells assessed as induction of VEGRF2 protein degradation at 1 uM preincubated with 4-Amino-N-(6-(1-(2-((4-methyl-3-(trifluoromethyl)phenyl)amino)-2-oxoethyl)-1H-pyrazol-4-y1)-1H-indazol-3-Abenzamide for 2 hrs followed by compound addition and measured after 24 hrs by Western blot analysis

Format: BAO_0000219

Organism: Homo sapiens

Cell type: HGC-27

Target:  VHL/Vascular endothelial growth factor receptor 2(ALA5291691)

Document:  ALA5247592

PROTAC activity at VHL/VEGFR2 in human HGC-27 cells assessed as induction of VEGRF2 protein degradation at 1 uM preincubated with 4-Amino-N-(6-(1-(2-((4-methyl-3-(trifluoromethyl)phenyl)amino)-2-oxoethyl)-1H-pyrazol-4-y1)-1H-indazol-3-Abenzamide for 2 hrs followed by compound addition and measured after 24 hrs by Western blot analysis: 1