Basic Information
ID: ALA5249117
Type: Binding
Description: PROTAC activity at VHL/VEGFR2 in human HGC-27 cells assessed as reduction in relative VEGRF2 expression level at 1 uM preincubated with 4-Amino-N-(6-(1-(2-((4-methyl-3-(trifluoromethyl)phenyl)amino)-2-oxoethyl)-1H-pyrazol-4-y1)-1H-indazol-3-Abenzamide for 2 hrs followed by compound addition and measured after 24 hrs by Western blot analysis
Organism: Homo sapiens
Cell type: HGC-27
Activity Charts
Bioactivity
Activity Types for Assay ALA5249117
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 1130.31 |