Basic Information
ID: ALA5249120
Type: Binding
Description: PROTAC activity at VHL/VEGFR2 in human HGC-27 cells assessed as induction of VEGRF2 protein degradation at 1 uM preincubated with MLN4924 for 2 hrs followed by compound addition and measured after 24 hrs by Western blot analysis
Format: BAO_0000219
Organism: Homo sapiens
Cell type: HGC-27
Target: VHL/Vascular endothelial growth factor receptor 2(ALA5291691)
Document: ALA5247592
PROTAC activity at VHL/VEGFR2 in human HGC-27 cells assessed as induction of VEGRF2 protein degradation at 1 uM preincubated with MLN4924 for 2 hrs followed by compound addition and measured after 24 hrs by Western blot analysis: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA5249120
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 1130.31 |