PROTAC activity at VHL/VEGFR2 in human HGC-27 cells assessed as reduction in relative VEGRF2 expression level at 1 uM preincubated with MG-132 for 2 h...

Basic Information

ID: ALA5249122

Type: Binding

Description: PROTAC activity at VHL/VEGFR2 in human HGC-27 cells assessed as reduction in relative VEGRF2 expression level at 1 uM preincubated with MG-132 for 2 hrs followed by compound addition and measured after 24 hrs by Western blot analysis

Format: BAO_0000219

Organism: Homo sapiens

Cell type: HGC-27

Target:  VHL/Vascular endothelial growth factor receptor 2(ALA5291691)

Document:  ALA5247592

PROTAC activity at VHL/VEGFR2 in human HGC-27 cells assessed as reduction in relative VEGRF2 expression level at 1 uM preincubated with MG-132 for 2 hrs followed by compound addition and measured after 24 hrs by Western blot analysis: 1

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
1130.31