Assay Report Card

Basic Information

ID: ALA5249325

Type: Functional

Description: Reversal of P-gp-mediated multidrug resistance in human NCI-ADR-RES cells assessed as change in ABCB1 expression level at 1 to 10 uM incubated for 48 hrs in presence of doxorubicin by Western blot analysis

Organism: Homo sapiens

Cell type: NCI/ADR-RES

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
814.975.875.87