Basic Information
ID: ALA5249644
Type: Binding
Description: Inhibition of human glutaminyl cyclase using L-glutamine-7-amido-4-methylcoumarin as substrate incubated for 10 mins in presence of pyroglutamyl peptidase by fluorometry analysis
Format: BAO_0000357
Organism: Homo sapiens
Target: Glutaminyl-peptide cyclotransferase(ALA4508)
Document: ALA5247605
Inhibition of human glutaminyl cyclase using L-glutamine-7-amido-4-methylcoumarin as substrate incubated for 10 mins in presence of pyroglutamyl peptidase by fluorometry analysis: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA5249644
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 334.45 | 2.59 | 2.59 |
| 336.40 | 3.62 | 3.62 |
| 434.52 | 4.33 | 4.33 |
| 434.52 | 4.33 | 4.33 |
| 312.38 | 2.59 | 2.59 |
| 423.57 | 3.09 | 3.09 |
| 460.59 | 4.06 | 4.06 |
| 403.49 | 3.58 | 3.58 |
| 422.58 | 4.57 | 4.57 |
| 420.49 | 4.32 | 4.32 |
| 417.52 | 3.59 | 3.59 |
| 408.55 | 4.33 | 4.33 |
| 417.52 | 3.59 | 3.59 |
| 312.38 | 2.59 | 2.59 |
| 406.46 | 4.01 | 4.01 |
| 326.40 | 2.60 | 2.60 |
| 434.52 | 4.33 | 4.33 |
| 460.59 | 4.06 | 4.06 |
| 417.52 | 3.59 | 3.59 |
| 434.52 | 4.33 | 4.33 |
| 394.52 | 4.32 | 4.32 |
| 438.58 | 2.31 | 2.31 |
| 408.55 | 4.18 | 4.18 |
| 409.54 | 3.08 | 3.08 |
| 394.52 | 4.32 | 4.32 |
| 448.55 | 4.90 | 4.90 |
| 420.49 | 4.02 | 4.02 |
| 417.52 | 3.59 | 3.59 |
| 394.52 | 4.17 | 4.17 |
| 394.52 | 4.17 | 4.17 |
| 408.55 | 4.33 | 4.33 |
| 438.58 | 2.31 | 2.31 |
| 408.55 | 4.18 | 4.18 |
| 420.49 | 4.32 | 4.32 |
| 326.40 | 2.60 | 2.60 |