Basic Information
ID: ALA5249650
Type: Functional
Description: Antialzheimer activity in human amyloid beta (3 to 40 residues) induced ICR mouse model assessed as inhibition of pyroglutamate form of amyloid-beta formation in brain at 10 mM, icv by sandwich ELISA relative to control
Format: BAO_0000218
Organism: Mus musculus
Strain: ICR
Target: Mus musculus(ALA375)
Document: ALA5247605
Antialzheimer activity in human amyloid beta (3 to 40 residues) induced ICR mouse model assessed as inhibition of pyroglutamate form of amyloid-beta formation in brain at 10 mM, icv by sandwich ELISA relative to control: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA5249650
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 336.40 | 3.62 | 3.62 |
| 434.52 | 4.33 | 4.33 |
| 420.49 | 4.32 | 4.32 |
| 434.52 | 4.33 | 4.33 |
| 460.59 | 4.06 | 4.06 |
| 394.52 | 4.32 | 4.32 |
| 394.52 | 4.32 | 4.32 |
| 394.52 | 4.17 | 4.17 |