Basic Information
ID: ALA5249942
Type: Binding
Description: Protac activity at CRBN/EGFR L858R/T790M/C797S mutant (unknown origin) expressed in mouse BaF3 cells assessed as degradation of EGFR L858R/T790M/C797S incubated for 24 hrs by Western blot analysis
Format: BAO_0000219
Organism: Homo sapiens
Cell type: BaF3
Target: Protein cereblon/Epidermal growth factor receptor(ALA4523680)
Document: ALA5247611
Protac activity at CRBN/EGFR L858R/T790M/C797S mutant (unknown origin) expressed in mouse BaF3 cells assessed as degradation of EGFR L858R/T790M/C797S incubated for 24 hrs by Western blot analysis: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA5249942
EC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 864.39 | 5.66 | 5.66 |