Basic Information
ID: ALA5250065
Type: Binding
Description: Inhibition of human NOX2 assessed as reduction in ROS production using lucigenin as substrate in presence of NADPH by chemiluminescence based microplate reader analysis
Format: BAO_0000357
Organism: Homo sapiens
Target: Cytochrome b-245 heavy chain(ALA1287627)
Document: ALA5247616
Inhibition of human NOX2 assessed as reduction in ROS production using lucigenin as substrate in presence of NADPH by chemiluminescence based microplate reader analysis: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA5250065
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 373.52 | 2.85 | 2.85 |
| 337.45 | 3.36 | 3.36 |
| 353.45 | 3.06 | 3.06 |
| 403.55 | 2.94 | 2.94 |
| 365.50 | 4.14 | 4.14 |
| 403.55 | 2.86 | 2.86 |
| 387.55 | 3.97 | 3.97 |
| 359.50 | 3.19 | 3.19 |
| 397.50 | 2.73 | 2.73 |
| 373.52 | 3.49 | 3.49 |
| 395.53 | 4.15 | 4.15 |
| 389.52 | 2.55 | 2.55 |
| 417.58 | 3.25 | 3.25 |
| 367.47 | 3.37 | 3.37 |
| 383.47 | 2.43 | 2.43 |
| 387.55 | 3.24 | 3.24 |
| 381.50 | 3.84 | 3.84 |
| 397.50 | 2.82 | 2.82 |
| 343.50 | 3.49 | 3.49 |
| 411.53 | 3.12 | 3.12 |
| 381.50 | 3.11 | 3.11 |
| 401.58 | 4.27 | 4.27 |
| 371.55 | 4.27 | 4.27 |
| 367.47 | 2.72 | 2.72 |