Basic Information
ID: ALA5250066
Type: ADME
Description: Metabolic stability in human liver microsomes assessed as parent compound remaining preincubated for 5 mins followed by NADPH addition and measured after 30 mins by LC-MS/MS analysis
Format: BAO_0000251
Organism: Homo sapiens
Tissue: Liver
Subcellular Fraction: Microsome
Target: ADMET(ALA612558)
Document: ALA5247616
Metabolic stability in human liver microsomes assessed as parent compound remaining preincubated for 5 mins followed by NADPH addition and measured after 30 mins by LC-MS/MS analysis: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA5250066
Stability
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 454.61 | 5.09 | 5.09 |
| 373.52 | 2.85 | 2.85 |
| 337.45 | 3.36 | 3.36 |
| 365.50 | 4.14 | 4.14 |
| 403.55 | 2.86 | 2.86 |
| 395.53 | 4.15 | 4.15 |
| 417.58 | 3.25 | 3.25 |
| 367.47 | 3.37 | 3.37 |
| 381.50 | 3.84 | 3.84 |