Basic Information
ID: ALA5250194
Type: Binding
Description: Inhibition of EGFR L858R/T790M/C797S triple mutant (unknown origin) expressed in Bac-to-Bac baculovirus expression system measured after 2 hrs by ELISA method
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA5250194
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 475.36 | 4.43 | 4.43 |
| 373.41 | 5.18 | 5.18 |
| 584.11 | 5.09 | 5.09 |
| 484.60 | 6.20 | 6.20 |
| 471.56 | 5.29 | 5.29 |
| 469.59 | 5.85 | 5.85 |
| 500.60 | 5.90 | 5.90 |
| 513.60 | 4.99 | 4.99 |
| 549.47 | 6.66 | 6.66 |
| 488.56 | 6.03 | 6.03 |
| 527.63 | 5.25 | 5.25 |
| 484.60 | 6.20 | 6.20 |
| 486.64 | 6.25 | 6.25 |
| 488.56 | 6.03 | 6.03 |
| 484.60 | 6.20 | 6.20 |
| 488.56 | 6.03 | 6.03 |
| 549.47 | 6.66 | 6.66 |
| 468.60 | 5.69 | 5.69 |
| 505.02 | 6.55 | 6.55 |
| 495.58 | 5.77 | 5.77 |
| 505.02 | 6.55 | 6.55 |
| 471.56 | 5.29 | 5.29 |
| 505.02 | 6.55 | 6.55 |
| 549.47 | 6.66 | 6.66 |
| 488.56 | 6.03 | 6.03 |
| 452.56 | 4.13 | 4.13 |
| 502.64 | 5.27 | 5.27 |
| 476.62 | 5.81 | 5.81 |
| 512.61 | 6.10 | 6.10 |
| 484.60 | 6.20 | 6.20 |
| 470.57 | 5.89 | 5.89 |
| 484.60 | 6.20 | 6.20 |
| 454.57 | 5.77 | 5.77 |
| 518.64 | 4.94 | 4.94 |
| 471.56 | 5.29 | 5.29 |
| 488.56 | 6.03 | 6.03 |
| 549.47 | 6.66 | 6.66 |
| 505.02 | 6.55 | 6.55 |