Basic Information
ID: ALA5250389
Type: Binding
Description: Protac activity at CRBN/BCR-ABL in human K562 cells assessed as increase in BCR-ABL degradation at 500 nM by Western blotting analysis
Organism: Homo sapiens
Cell type: K562
Activity Charts
Bioactivity
Activity Types for Assay ALA5250389
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 273.25 | -0.33 | -0.33 |
| 259.26 | 0.03 | 0.03 |
| 449.85 | 3.46 | 3.46 |
| 776.20 | 4.19 | 4.19 |
| 762.13 | 3.05 | 3.05 |
| 804.21 | 4.22 | 4.22 |
| 807.24 | 4.51 | 4.51 |
| 777.19 | 4.16 | 4.16 |
| 864.26 | 3.48 | 3.48 |
| 809.25 | 4.11 | 4.11 |
| 790.18 | 3.83 | 3.83 |
| 832.26 | 5.00 | 5.00 |
| 793.25 | 4.87 | 4.87 |
| 818.24 | 4.61 | 4.61 |
| 791.17 | 3.80 | 3.80 |
| 952.37 | 3.51 | 3.51 |
| 799.19 | 4.16 | 4.16 |