Basic Information
ID: ALA5250390
Type: Binding
Description: Protac activity at CRBN/BCR-ABL in human K562 cells assessed as increase in BCR-ABL degradation at 5 nM by Western blotting analysis
Organism: Homo sapiens
Cell type: K562
Activity Charts
Bioactivity
Activity Types for Assay ALA5250390
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 904.48 | 6.98 | 6.98 |
| 876.43 | 6.20 | 6.20 |
| 807.32 | 6.13 | 6.13 |
| 807.32 | 6.17 | 6.17 |
| 848.38 | 5.42 | 5.42 |
| 710.16 | 5.64 | 5.64 |
| 763.20 | 4.63 | 4.63 |
| 821.35 | 6.56 | 6.56 |
| 882.41 | 6.24 | 6.24 |
| 890.46 | 6.59 | 6.59 |
| 874.39 | 5.88 | 5.88 |
| 862.40 | 5.81 | 5.81 |
| 876.39 | 5.45 | 5.45 |
| 765.24 | 4.96 | 4.96 |
| 779.27 | 5.35 | 5.35 |
| 771.23 | 5.00 | 5.00 |
| 738.22 | 6.42 | 6.42 |
| 724.19 | 6.03 | 6.03 |
| 793.30 | 5.78 | 5.78 |