ID: ALA5250408
Type: Binding
Description: Protac activity at CRBN/BCR-ABL in human K562 cells assessed as induction of c-ABL degradation at 100 nM pretreated with asciminib for 2 hrs followed by compound addition measured after 8 hrs by Western blotting analysis
Organism: Homo sapiens
Cell type: K562
Bioactivity
Activity Types for Assay ALA5250408
Activity
Parent Molecular Weight | ALogP | Polar Surface Area |
---|---|---|
890.46 | 6.59 | 6.59 |