Assay Report Card

Basic Information

ID: ALA5250409

Type: Binding

Description: Protac activity at CRBN/BCR-ABL in human K562 cells assessed as induction of c-ABL degradation at 100 nM pretreated with MLN4924 for 2 hrs followed by compound addition measured after 8 hrs by Western blotting analysis

Organism: Homo sapiens

Cell type: K562

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
890.466.596.59