Assay Report Card

Basic Information

ID: ALA5250416

Type: Binding

Description: Protac activity at CRBN/BCR-ABL in human K562 cells assessed as increase in BCR-ABL degradation at 100 nM incubated for 6 hrs followed by compound washout measured upto 96 hrs by Western blotting analysis

Organism: Homo sapiens

Cell type: K562

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
904.486.936.93
890.466.596.59