Basic Information
ID: ALA5250616
Type: Binding
Description: Inhibition of C-terminal His6-tagged recombinant SARS-CoV-2 MPro transfected in Escherichia coli BL21 (DE3) using Dabcyl-KTSAVLQSGFRKM-E(Edans)-NH2 as substrate preincubated for 15 mins followed by substrate addition measured after 30 mins by FRET assay
Organism: Severe acute respiratory syndrome coronavirus 2
Activity Charts
Bioactivity
Activity Types for Assay ALA5250616
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 362.47 | 3.20 | 3.20 |
| 375.39 | -1.78 | -1.78 |
| 445.52 | -0.37 | -0.37 |
| 435.49 | -0.20 | -0.20 |
| 421.54 | 2.16 | 2.16 |
| 385.42 | -0.50 | -0.50 |
| 401.42 | -0.79 | -0.79 |
| 469.59 | 1.84 | 1.84 |
| 443.50 | 0.89 | 0.89 |
| 401.42 | -0.79 | -0.79 |