Assay Report Card

Basic Information

ID: ALA5250622

Type: Binding

Description: Binding affinity to C-terminal His6-tagged recombinant SARS-CoV-2 MPro transfected in Escherichia coli BL21 (DE3) assessed as dissociation constant by Cheng-Prusoff equation analysis

Organism: Severe acute respiratory syndrome coronavirus 2

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
362.473.203.20
375.39-1.78-1.78
445.52-0.37-0.37
435.49-0.20-0.20
421.542.162.16
385.42-0.50-0.50
401.42-0.79-0.79
469.591.841.84
443.500.890.89
401.42-0.79-0.79