Basic Information
ID: ALA5251210
Type: ADME
Description: Time dependent inhibition of CYP3A4 in human liver microsomes using midazolam as substrate preincubation of enzyme in the presence of NADP for 30 mins by LC-MS/MS analysis
Organism: Homo sapiens
Tissue: Liver
Subcellular Fraction: Microsome
Activity Charts
Bioactivity
Activity Types for Assay ALA5251210
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 507.58 | 4.98 | 4.98 |