Basic Information
ID: ALA5251277
Type: Binding
Description: Inhibition of recombinant LSD1 (unknown origin) expressed in Escherichia coli BL21 (DE3) using H3K4me2 peptide as substrate incubated for 30 mins by fluorescence based microplate reader assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA5251277
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 318.87 | 4.89 | 4.89 |
| 284.43 | 4.24 | 4.24 |
| 352.43 | 5.26 | 5.26 |
| 340.49 | 4.40 | 4.40 |
| 339.51 | 3.93 | 3.93 |
| 270.40 | 3.85 | 3.85 |
| 401.58 | 5.50 | 5.50 |
| 303.28 | 2.40 | 2.40 |
| 325.48 | 3.54 | 3.54 |
| 351.50 | 5.26 | 5.26 |
| 415.61 | 5.50 | 5.50 |
| 324.49 | 5.02 | 5.02 |
| 367.52 | 3.84 | 3.84 |
| 405.52 | 4.34 | 4.34 |
| 353.49 | 3.45 | 3.45 |
| 326.47 | 4.01 | 4.01 |
| 380.44 | 4.64 | 4.64 |
| 355.51 | 3.21 | 3.21 |
| 354.52 | 4.79 | 4.79 |
| 367.56 | 4.75 | 4.75 |
| 358.53 | 4.34 | 4.34 |
| 389.53 | 3.90 | 3.90 |
| 393.60 | 5.24 | 5.24 |
| 326.47 | 4.01 | 4.01 |
| 368.55 | 3.13 | 3.13 |
| 367.56 | 4.71 | 4.71 |
| 327.45 | 3.13 | 3.13 |
| 328.51 | 4.34 | 4.34 |
| 337.47 | 4.87 | 4.87 |
| 327.50 | 3.83 | 3.83 |
| 389.55 | 2.87 | 2.87 |
| 342.53 | 4.73 | 4.73 |
| 401.58 | 5.11 | 5.11 |
| 411.57 | 4.84 | 4.84 |
| 311.45 | 3.19 | 3.19 |
| 342.46 | 3.63 | 3.63 |
| 338.52 | 5.41 | 5.41 |
| 346.88 | 4.27 | 4.27 |
| 345.49 | 4.59 | 4.59 |
| 353.54 | 4.32 | 4.32 |
| 369.53 | 3.60 | 3.60 |
| 459.62 | 5.23 | 5.23 |
| 325.48 | 3.58 | 3.58 |
| 351.52 | 4.07 | 4.07 |
| 339.51 | 3.93 | 3.93 |
| 353.54 | 4.32 | 4.32 |
| 383.56 | 3.99 | 3.99 |
| 312.44 | 3.62 | 3.62 |