ID: ALA5251559
Type: ADME
Description: Metabolic stability in human liver microsomes assessed as intrinsic clearance at 1 uM and measured upto 15 mins in presence of NADPH regenerating system by LC-MS/MS analysis
Organism: Homo sapiens
Tissue: Liver
Subcellular Fraction: Microsome
Bioactivity
Activity Types for Assay ALA5251559
CL
Parent Molecular Weight | ALogP | Polar Surface Area |
---|---|---|
549.50 | 3.11 | 3.11 |
578.54 | 3.45 | 3.45 |
549.50 | 3.24 | 3.24 |
536.46 | 2.25 | 2.25 |
564.52 | 3.06 | 3.06 |
564.52 | 2.89 | 2.89 |
550.49 | 2.50 | 2.50 |
550.49 | 2.64 | 2.64 |
536.46 | 2.25 | 2.25 |
578.54 | 3.45 | 3.45 |
535.47 | 2.85 | 2.85 |
563.53 | 3.50 | 3.50 |
550.49 | 2.64 | 2.64 |
562.50 | 2.82 | 2.82 |
564.52 | 2.89 | 2.89 |
549.50 | 3.24 | 3.24 |
550.49 | 2.50 | 2.50 |
576.53 | 3.21 | 3.21 |
564.52 | 3.06 | 3.06 |
535.47 | 2.85 | 2.85 |