Basic Information
ID: ALA5251561
Type: ADME
Description: Induction of recombinant human CYP3A4 mediated drug metabolism in human liver microsomes assessed as intrinsic clearance at 1 uM incubated for 45 mins in presence of NADPH regenerating system by LC-MS/MS analysis
Organism: Homo sapiens
Tissue: Liver
Subcellular Fraction: Microsome
Activity Charts
Bioactivity
Activity Types for Assay ALA5251561
CL
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 534.49 | 3.58 | 3.58 |
| 578.54 | 3.45 | 3.45 |
| 549.50 | 3.24 | 3.24 |
| 564.52 | 3.06 | 3.06 |
| 564.52 | 2.89 | 2.89 |
| 535.47 | 2.85 | 2.85 |
| 550.49 | 2.64 | 2.64 |
| 550.49 | 2.50 | 2.50 |
| 535.47 | 2.85 | 2.85 |