ID: ALA5251606
Type: Functional
Description: In vivo antagonist activity at CXCR3 in LPS-induced DBA/1 mouse model assessed as reduction in mouse CXCL10-mediated chemotaxis in CD8+ T cells at 0.006 microg/g, po bid preincubated for 3 days followed by LPS stimulation for 30 mins and measured after 3 days by flow cytometry
Organism: Mus musculus
Strain: DBA/1
Cell type: T-cell
Bioactivity
Activity Types for Assay ALA5251606
Activity
Parent Molecular Weight | ALogP | Polar Surface Area |
---|---|---|
550.49 | 2.64 | 2.64 |