Assay Report Card

Basic Information

ID: ALA5251606

Type: Functional

Description: In vivo antagonist activity at CXCR3 in LPS-induced DBA/1 mouse model assessed as reduction in mouse CXCL10-mediated chemotaxis in CD8+ T cells at 0.006 microg/g, po bid preincubated for 3 days followed by LPS stimulation for 30 mins and measured after 3 days by flow cytometry

Organism: Mus musculus

Strain: DBA/1

Cell type: T-cell

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
550.492.642.64