Basic Information
ID: ALA5251710
Type: Functional
Description: Reversal of VCR -resistance in human Eca-109 cells assessed as vincristine IC50 by measuring cell viability incubated for 48 hrs by CCK-8 method (Rvb = 6830.0+/-537.0 nM)
Organism: Homo sapiens
Cell type: ECa-109 cell line
Activity Charts
Bioactivity
Activity Types for Assay ALA5251710
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 454.61 | 5.09 | 5.09 |
| 646.74 | 6.37 | 6.37 |
| 622.76 | 7.16 | 7.16 |
| 357.45 | 3.49 | 3.49 |
| 341.41 | 3.20 | 3.20 |
| 263.38 | 3.28 | 3.28 |
| 313.40 | 3.18 | 3.18 |
| 327.42 | 3.48 | 3.48 |
| 221.26 | 1.33 | 1.33 |
| 207.27 | 1.69 | 1.69 |
| 343.42 | 3.19 | 3.19 |
| 436.35 | 4.26 | 4.26 |
| 343.42 | 3.19 | 3.19 |
| 341.41 | 3.07 | 3.07 |
| 235.33 | 2.64 | 2.64 |
| 439.60 | 5.44 | 5.44 |
| 299.37 | 2.99 | 2.99 |
| 413.56 | 4.91 | 4.91 |
| 313.40 | 3.18 | 3.18 |
| 371.48 | 3.88 | 3.88 |
| 331.84 | 4.13 | 4.13 |
| 331.84 | 4.13 | 4.13 |
| 365.40 | 4.49 | 4.49 |
| 221.30 | 2.25 | 2.25 |
| 297.40 | 3.48 | 3.48 |
| 342.40 | 3.38 | 3.38 |
| 331.84 | 4.13 | 4.13 |
| 161.20 | 1.31 | 1.31 |
| 453.62 | 5.83 | 5.83 |
| 423.29 | 4.08 | 4.08 |
| 303.45 | 4.20 | 4.20 |
| 322.41 | 3.35 | 3.35 |
| 453.62 | 5.83 | 5.83 |
| 509.65 | 6.63 | 6.63 |
| 315.39 | 3.61 | 3.61 |
| 313.40 | 3.18 | 3.18 |
| 457.57 | 4.21 | 4.21 |
| 240.10 | 2.08 | 2.08 |
| 311.43 | 3.78 | 3.78 |
| 441.57 | 4.29 | 4.29 |
| 376.29 | 4.24 | 4.24 |
| 289.30 | 3.19 | 3.19 |
| 433.55 | 5.06 | 5.06 |