Assay Report Card

Basic Information

ID: ALA5251757

Type: Functional

Description: Synergistic antitumor activity against in vincristine resistant p-gp overexpressing human Eca-109 cells xenografted in nude mouse assessed as increase in nuclear pyknosis at 30 mg/kg, IG administered every two days for 21 days in presence of vincristine by TUNEL analysis

Organism: Homo sapiens

Cell type: ECa-109 cell line

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
433.555.065.06