Assay Report Card

Basic Information

ID: ALA5251795

Type: Binding

Description: PROTAC activity at VHL/SOS1 in human NCI-H358 cells assessed as induction of SOS1 protein degradation at 0.1 uM incubated for 24 hrs by Immunoblot analysis relative to control

Organism: Homo sapiens

Cell type: NCI-H358

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
1014.27
1084.36
1028.30
1041.26
1030.23
1046.23
1056.31
1040.27
1014.23
1030.23
1069.31
1028.26
1000.20
1030.23
1070.34
1042.28
1000.25