Basic Information
ID: ALA5251800
Type: Binding
Description: PROTAC activity at VHL/SOS1 in human NCI-H358 cells assessed as induction of SOS1 protein degradation by measuring maximal efficacy at 2 to 2000 nM incubated for 24 hrs by Immunoblot analysis relative to control
Organism: Homo sapiens
Cell type: NCI-H358
Activity Charts
Bioactivity
Activity Types for Assay ALA5251800
Emax
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 1014.27 | ||
| 1030.23 | ||
| 1014.23 | ||
| 1030.23 | ||
| 1028.26 | ||
| 1030.23 | ||
| 1042.28 |