Assay Report Card

Basic Information

ID: ALA5251803

Type: Binding

Description: Binding affinity to GST-tagged human SOS1 (564 to 1049 residues) expressed in Escherichia coli BL21 (DE3) cells assessed as ternary complex formation by measuring dissociation constant incubated for 15 mins in the presence of 6His tagged human VCB by fluorescence polarization-based displacement assay

Organism: Homo sapiens

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
1014.27
1030.23
501.555.455.45
1014.23
1030.23
1028.26
1030.23
1042.28