Assay Report Card

Basic Information

ID: ALA5251805

Type: Binding

Description: PROTAC activity at VHL/SOS1 in human NCI-H358 cells harboring KRAS G12C mutant assessed as induction of SOS1 degradation upto 10 uM incubated for 24 hrs by immunoblotting analysis

Organism: Homo sapiens

Cell type: NCI-H358

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
1028.26