Basic Information
ID: ALA5251807
Type: Binding
Description: PROTAC activity at VHL/SOS1 in human NCI-H358 cells harboring KRAS G12C mutant with shRNA lentivirus mediated VHL knockdown assessed as induction of SOS1 degradation at 1 uM incubated for 24 hrs by Immunoblot analysis
Organism: Homo sapiens
Cell type: NCI-H358
Activity Charts
Bioactivity
Activity Types for Assay ALA5251807
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 1028.26 |