Assay Report Card

Basic Information

ID: ALA5251808

Type: Binding

Description: PROTAC activity at VHL/SOS1 in human ASPC1 cells harboring KRAS G12D mutant with shRNA lentivirus mediated VHL knockdown assessed as induction of SOS1 degradation at 1 uM incubated for 24 hrs by Immunoblot analysis

Organism: Homo sapiens

Cell type: ASPC1

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
1028.26