Basic Information
ID: ALA5251809
Type: Binding
Description: PROTAC activity at VHL/SOS1 in human NCI-H358 cells harboring KRAS G12C mutant assessed as induction of SOS1 degradation at 1 uM preincubated with VHL ligand for 4 hrs followed by compound treatment and measured after 24 hrs by Immunoblot analysis
Organism: Homo sapiens
Cell type: NCI-H358
Activity Charts
Bioactivity
Activity Types for Assay ALA5251809
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 1028.26 |