Basic Information
ID: ALA5251845
Type: Binding
Description: PROTAC activity at VHL/SOS1 in human NCI-H441 cells harboring KRAS G12V mutant assessed as induction of SOS1 degradation by measuring maximal efficacy at 1 to 2000 nM incubated for 24 hrs by Immunoblot analysis relative to control
Organism: Homo sapiens
Cell type: NCI-H441
Activity Charts
Bioactivity
Activity Types for Assay ALA5251845
Emax
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 1028.26 |