Basic Information
ID: ALA5251848
Type: Binding
Description: PROTAC activity at VHL/SOS1 in human HCT-116 cells harboring KRAS G13D mutant assessed as induction of SOS1 degradation by measuring maximal efficacy at 1 to 2000 nM incubated for 24 hrs by Immunoblot analysis relative to control
Format: BAO_0000219
Organism: Homo sapiens
Cell type: HCT-116
Target: VHL/SOS1(ALA5169070)
Document: ALA5247656
PROTAC activity at VHL/SOS1 in human HCT-116 cells harboring KRAS G13D mutant assessed as induction of SOS1 degradation by measuring maximal efficacy at 1 to 2000 nM incubated for 24 hrs by Immunoblot analysis relative to control: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA5251848
Emax
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 1028.26 |