Basic Information
ID: ALA5251859
Type: Binding
Description: PROTAC activity at VHL/SOS1 in human NCI-H358 cells harboring KRAS G12C mutant assessed as induction of SOS1 degradation at 1 uM incubated for 2 to 4 hrs by Immunoblot analysis
Format: BAO_0000219
Organism: Homo sapiens
Cell type: NCI-H358
Target: VHL/SOS1(ALA5169070)
Document: ALA5247656
PROTAC activity at VHL/SOS1 in human NCI-H358 cells harboring KRAS G12C mutant assessed as induction of SOS1 degradation at 1 uM incubated for 2 to 4 hrs by Immunoblot analysis: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA5251859
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 1028.26 |