ID: ALA5251862
Type: Binding
Description: PROTAC activity at VHL/SOS1 in human HCT-116 cells harboring KRAS G13D mutant assessed as induction of SOS1 degradation at 1 uM incubated for 2 to 4 hrs by Immunoblot analysis
Format: BAO_0000219
Organism: Homo sapiens
Cell type: HCT-116
Target: VHL/SOS1(ALA5169070)
Document: ALA5247656
PROTAC activity at VHL/SOS1 in human HCT-116 cells harboring KRAS G13D mutant assessed as induction of SOS1 degradation at 1 uM incubated for 2 to 4 hrs by Immunoblot analysis: 1
Bioactivity
Activity Types for Assay ALA5251862
Activity
Parent Molecular Weight | ALogP | Polar Surface Area |
---|---|---|
1028.26 |